- Article
Authors: Vu, Duc Loi; Bui, Thanh Tung; Nguyen, Huu Tung; Nguyen, Thanh Hai; Nguyen, Thuc Thu Huong; Nguyen, Tien Vung (2015) - The roots of Aconitum Carmichaeli Debx. is recognized as a medicinal plant by its anti-inflammatory and analgesic effects.
Our phytochemical investigation of the roots led to the isolation of three alkaloids including delcosine (1), fuziline (2), and
karacoline (3). Their structures were identified on the basis of NMR, MS, IR spectroscopic analysis and comparison with
the published NMR data. Compound 1 was isolated for the first time from this plant
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- Article
Authors: Bui, Thi Xuan; Vu, Duc Loi; Pham, Thi Ha; Tran, Minh Ngoc; Bui, Thi Kim Dung (2019) - The ethylacetate fraction of the leaf of Sanchezia nobilis Hook.f. collected in Nam Dinh province isolated two compounds, daucosterol and stigmasterol, for the first time by chromatographic methods. Their structures were elucidated by spectroscopic methods, including MS and NMR
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- Article
Authors: Nguyen, Thanh Hai; Le, Tuan Anh; Duong, Thi Ly Huong; Nguyen, Huu Tung; Vu, Duc Loi; Dang, Thu Kim; Bui, Thanh Tung (2015) - Objective: To investigated the protective potential of ethanol extracts of Scutellaria baicalensis
(S. baicalensis) against lipopolysaccharide (LPS)-induced liver injury.
Methods:Dried roots of S. baicalensiswere extracted with ethanol and concentrated to yield
a dry residue. Mice were administered 200 mg/kg of the ethanol extracts orally once daily for
one week. Animals were subsequently administered a single dose of LPS(5 mg/kg of body
weight, intraperitoneal injection). Both protein and mRNAlevels of cytokines, such as tumor
necrosis factor alpha, interleukin-1β, and interleukin-6 in liver tissues were evaluated by ELISA
assay and quantitative PCR. Cyclooxygenase-2, ind...
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- Article
Authors: Vu, Duc Loi; Bui, Thanh Tung; Nguyen, Thanh Hai; Nguyen, Tien Vung (2015) - Two flavonol glycosides: 5,7,3
'
-trimethoxyquercetin -3-O-β-D-fructofuranoside (1), 7,4′-O-dimethylluteolin 5-O-[α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside] (2) and one fatty acid ester (Z)-3-hydroxypentan-2-yl-10-aminooctacos-9-enoate (3) were isolated from the leaves of Aconitum carmichaeli Debx growing in Ha Giang
province, Vietnam. Their structures were elucidatedby spectroscopic methods, including IR, MS and NMR. This is
first time these compounds were isolated from leaves of A. carmichaeli Debx.
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- Article
Authors: Bui, Thanh Tung; Nguyen, Hai Thanh; Duong, Thi Ly Huong; Le, Thi Thu Huong; Vu, Duc Loi; Nguyen, Huu Tung (2015) - Tetracera scandens L. (Dilleniaceae) is a genus of flowering plants of the Dilleniaceae family. It has been reported
that Tetracera scandens L. content hight amout of flavonoids. From the ethanol extract of leaves of Tetracera
scandens L, we have been isolated six known flavonoids compounds. Their structures were identified as quercetin-3-O-L-rhamnoside (1), genistein (2), quercetin (3), quercetin 3-O-β-D-glucuronide (4), kaempferol (5) and
quercetin-3-O-α-L-arabinofuranoside (6) on the basis of spectroscopic data and by comparing their
physicochemical and spectral data with those published in literatures
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- Article
Authors: Vu, Duc Loi; Bui, Thanh Tung; Nguyen, Tien Vung (2016) - Nerium oleander L. is an evergreen shrub in the dogbane family Apocynaceae and planted
throughout the tropical region. It has cardiotonic, antioxidant, anti-inflammatory and anticancer
activities.Nerium oleanderL. has high amount of cardiac glycoside and flavonoids compounds.
From methanol extract of flowers of Nerium oleanderL. grown in vietnam, it has been isolated four
compounds. Their structures were identified as (1) D
16
-Dehydroadynerigenin, (2) D
16
-Digitoxigenin,
(3) Quercetin and (4) Kaempferol on the basis of spectroscopic data and by comparing their
physicochemical and spectral data with those published studies. The effect of fraction HF2, which
containing comp...
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- Thesis
Authors: Trinh, Van Hoan; Vu, Duc Loi (2011) - Tìm hiểu các phương pháp phân tích hàm lượng tổng thuỷ ngân và dạng thuỷ ngân hiện đang áp dụng trên thế giới. Nghiên cứu các điều kiện tối ưu trong quá trình xử lý mẫu, ghi đo phổ để nâng cao độ nhạy, độ chọn lọc và độ chính xác của phương pháp xác định các dạng thuỷ ngân vô cơ và hữu cơ trong trầm tích. Áp dụng các quy trình tách, phân tích hàm lượng các dạng thủy ngân vô cơ, thủy ngân hữu cơ và thủy ngân tổng số trong trầm tích. Nhận xét thực trạng ô nhiễm thủy ngân lưu vực sông Nhuệ và sông Đáy.
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- Article
Authors: Nguyen, Thanh Hai; Pham, Thi Minh Hue; Vu, Duc Loi; Bui, Thanh Tung (2016) - We investigate the effects of Coenzyme Q10 (CoQ10) supplementation on methamphetamine
(METH)-induced neurotoxicity in the mouse brain. We used 30 mice divided into three groups
containing 10 animals each: a control group, a brain injury group treated with METH and a group
treated with METH+CoQ10. Various assays, such as protein thiol group, glutathione total, lipid
peroxidation, catalase, superoxide dismutase and glutathione peroxidase, were used to assess the
damage caused by METH and the protective effects of CoQ10 on brain tissues. The METH-induced
brain injury significantly increased lipid peroxidation and decreased the level of the thiol group,
the glutathione total and th...
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