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Browsing by Author Hoang, Van Tuyen

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  • Construction of Yeast Pichia pastoris Expressing the Recombinant p53 as a Secreted Protein into Culture

    • Authors: Tran, Thi Thuy Nga; Nguyen, Quang Hoa; Hoang, Van Tuyen; Do, Thi Tuyen; Dinh, Nho Thai (2016)

  • Human p53 protein has been known as a tumor suppressor and described as "the guardian of the genome", referring to its role in conserving stability of genome by preventing mutation. The recent studies on p53 protein expression have demonstrated the important role and effectiveness of exogenous p53 protein in tumor suppression. In the world, the expression of p53 for therapeutically interest was extensively study but in Vietnam it has not been noticed. In the other hand, Pichia pastoris showed a good expression system for many exogenous proteins with a simple cloning work and cheap culture. In this study, codon optimization of gene encoding human p53 protein was performed for suitable ...

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Browsing by Author Hoang, Van Tuyen

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 2 of 2
  • document(47).pdf.jpg
  • Article

  • Construction of Yeast Pichia pastoris Expressing the Recombinant p53 as a Secreted Protein into Culture

    • Authors: Tran, Thi Thuy Nga; Nguyen, Quang Hoa; Hoang, Van Tuyen; Do, Thi Tuyen; Dinh, Nho Thai (2016)

  • Human p53 protein has been known as a tumor suppressor and described as "the guardian of the genome", referring to its role in conserving stability of genome by preventing mutation. The recent studies on p53 protein expression have demonstrated the important role and effectiveness of exogenous p53 protein in tumor suppression. In the world, the expression of p53 for therapeutically interest was extensively study but in Vietnam it has not been noticed. In the other hand, Pichia pastoris showed a good expression system for many exogenous proteins with a simple cloning work and cheap culture. In this study, codon optimization of gene encoding human p53 protein was performed for suitable ...