Browsing by Author Nguyen, Dinh Thang

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  • Authors: Pham, Ngoc Diep; Nguyen, Lai Thanh; Nguyen, Dinh Thang (2016)

  • In this study, we investigated the effects of Polygonum multiflorum (PM) root extract in methanol on developments of teratogenic defects as well as the changing of transcript levels of molecules related to melanin formation in embryos of wild type strain AB zebrafish. Our results showed that PM root extract contributed an important role in melanin formation in zebrafish embryos via activation of MC1R/MITF/tyrosinase pathway. However we also found that, at the high concentration (above 225 mg/L), PM root extract acted as an agent for developments of teratogenic defects, including: heart/yolk-sac oedema, haemovascular defect with appearing of red dots accumulation; yolk/head/body necros...

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  • Article


  • Authors: Nguyen, Thi Bich; Bui, Thi Van Khanh; Truong, Linh Huyen; Chu, Thi Thao; Bui, Viet Anh; Nguyen, Dinh Thang; Nguyen, Thanh Liem; Hoang, Thi My Nhung (2016)

  • Mesenchymal stem cell (MSC) is a promising source of novel cell-based therapies, driven by the hope of finding cures for numerous diseases including skin wound healing. In this study, we isolated MSCs from Wharton’s jelly of human umbilical cord by enzymatic method. To determine the effect of MSC conditioned medium on wound healing ability, we examined two MSC conditioned mediums (MSC-CM), which differ in concentration of serum and harvest time. The results showed that in serum starvation condition, MSC-CM showed significantly enhanced keratinocyte migration speed and prolonged culture of MSC in this condition also improve the efficiency of MSC-CM.

  • document(45).pdf.jpg
  • Article


  • Authors: Nguyen, Thi Le Na; Pham, Thi Hoa; Nguyen, Dinh Thang (2016)

  • Development of materials for treatment of heavy metals and bacteria in aqueous solution is still on the way. Although there are many materials developed, there is limit material which could be practical applied to eliminate a wide range of heavy metal ions and bacteria in drinking water. In this study, we investigated the adsorption capacity of melanin extracted from the ink sacs of squids toward heavy metals (chromium and manganese), which normally presented at high concentrations in water sources originated from mining, metal plating and steel making industries, as well as bacteria in aqueous solution. Our results showed that melanin could remove Cr6+ and Mn2+ effectively (> 97%) w...

Browsing by Author Nguyen, Dinh Thang

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 3 of 3
  • document(18).pdf.jpg
  • Article


  • Authors: Pham, Ngoc Diep; Nguyen, Lai Thanh; Nguyen, Dinh Thang (2016)

  • In this study, we investigated the effects of Polygonum multiflorum (PM) root extract in methanol on developments of teratogenic defects as well as the changing of transcript levels of molecules related to melanin formation in embryos of wild type strain AB zebrafish. Our results showed that PM root extract contributed an important role in melanin formation in zebrafish embryos via activation of MC1R/MITF/tyrosinase pathway. However we also found that, at the high concentration (above 225 mg/L), PM root extract acted as an agent for developments of teratogenic defects, including: heart/yolk-sac oedema, haemovascular defect with appearing of red dots accumulation; yolk/head/body necros...

  • document(17).pdf.jpg
  • Article


  • Authors: Nguyen, Thi Bich; Bui, Thi Van Khanh; Truong, Linh Huyen; Chu, Thi Thao; Bui, Viet Anh; Nguyen, Dinh Thang; Nguyen, Thanh Liem; Hoang, Thi My Nhung (2016)

  • Mesenchymal stem cell (MSC) is a promising source of novel cell-based therapies, driven by the hope of finding cures for numerous diseases including skin wound healing. In this study, we isolated MSCs from Wharton’s jelly of human umbilical cord by enzymatic method. To determine the effect of MSC conditioned medium on wound healing ability, we examined two MSC conditioned mediums (MSC-CM), which differ in concentration of serum and harvest time. The results showed that in serum starvation condition, MSC-CM showed significantly enhanced keratinocyte migration speed and prolonged culture of MSC in this condition also improve the efficiency of MSC-CM.

  • document(45).pdf.jpg
  • Article


  • Authors: Nguyen, Thi Le Na; Pham, Thi Hoa; Nguyen, Dinh Thang (2016)

  • Development of materials for treatment of heavy metals and bacteria in aqueous solution is still on the way. Although there are many materials developed, there is limit material which could be practical applied to eliminate a wide range of heavy metal ions and bacteria in drinking water. In this study, we investigated the adsorption capacity of melanin extracted from the ink sacs of squids toward heavy metals (chromium and manganese), which normally presented at high concentrations in water sources originated from mining, metal plating and steel making industries, as well as bacteria in aqueous solution. Our results showed that melanin could remove Cr6+ and Mn2+ effectively (> 97%) w...