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dc.contributor.authorLe, Thi Tuyet-
dc.contributor.authorTran, Quang Binh-
dc.date.accessioned2019-01-14T08:17:45Z-
dc.date.available2019-01-14T08:17:45Z-
dc.date.issued2018-
dc.identifier.citationLe, T. T., Tran, Q. B. (2018). Associations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoi. VNU Journal of Science: Medical and Pharmaceutical Sciences, Vol. 34, No. 2 (2018) 1vi
dc.identifier.issn2588-1132-
dc.identifier.urihttp://repository.vnu.edu.vn/handle/VNU_123/63617-
dc.description.abstractMelanocortin-4 receptor (MC4R) plays roles in regulating food intake and energy balance. A number of studies have revealed that variant rs17782313 is significantly associated with obesity in different populations. However, their contribution to obesity in the Vietnamese populations have not been described. This study was aimed at evaluating the association of rs17782313 with anthropometric indices and obesity in the Vietnamese childrens. A case-control study was conducted on 559 children aged 6-11 years (278 obese cases and 281 normal controls). The nutrition status of the children was classified using both criteria of the International Obesity Task Force 2000 and the World Health Organization 2007. The results showed that in normal group, the data of z score of weight for age was highest in CC genotype group and was lowest in TT genotype group (0.11 and -0.38, respectively, p=0.023). In obese group, the waist hip ratio was lowest in TT genotype group and the highest one was in CC genotype group (0.93 and 0.97 respectively, p=0.031). Our findings indicate that the variant rs17782313 near MC4R is likely to have an impact on the changing of weight and central obesity in the Vietnamese children.vi
dc.language.isoenvi
dc.publisherH. : ĐHQGHNvi
dc.relation.ispartofseriesVNU Journal of Science: Medical and Pharmaceutical Sciences;-
dc.subjectObesityvi
dc.subjectAnthropometric indicesvi
dc.subjectVietnamese childrenvi
dc.subjectMC4Rvi
dc.titleAssociations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoivi
dc.title.alternativeMối liên quan giữa đa hình đơn nucleotide rs17782313 của gen Melanocortin 4 Receptor với một số chỉ số nhân trắc của trẻ tiểu học bình thường và béo phì ở Hà Nộivi
dc.typeArticlevi
dc.identifier.doihttps:// doi.org/10.25073/2588-1132/vnumps.4107-
Appears in Collections:Medical and Pharmaceutical Sciences


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  • Full metadata record
    DC FieldValueLanguage
    dc.contributor.authorLe, Thi Tuyet-
    dc.contributor.authorTran, Quang Binh-
    dc.date.accessioned2019-01-14T08:17:45Z-
    dc.date.available2019-01-14T08:17:45Z-
    dc.date.issued2018-
    dc.identifier.citationLe, T. T., Tran, Q. B. (2018). Associations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoi. VNU Journal of Science: Medical and Pharmaceutical Sciences, Vol. 34, No. 2 (2018) 1vi
    dc.identifier.issn2588-1132-
    dc.identifier.urihttp://repository.vnu.edu.vn/handle/VNU_123/63617-
    dc.description.abstractMelanocortin-4 receptor (MC4R) plays roles in regulating food intake and energy balance. A number of studies have revealed that variant rs17782313 is significantly associated with obesity in different populations. However, their contribution to obesity in the Vietnamese populations have not been described. This study was aimed at evaluating the association of rs17782313 with anthropometric indices and obesity in the Vietnamese childrens. A case-control study was conducted on 559 children aged 6-11 years (278 obese cases and 281 normal controls). The nutrition status of the children was classified using both criteria of the International Obesity Task Force 2000 and the World Health Organization 2007. The results showed that in normal group, the data of z score of weight for age was highest in CC genotype group and was lowest in TT genotype group (0.11 and -0.38, respectively, p=0.023). In obese group, the waist hip ratio was lowest in TT genotype group and the highest one was in CC genotype group (0.93 and 0.97 respectively, p=0.031). Our findings indicate that the variant rs17782313 near MC4R is likely to have an impact on the changing of weight and central obesity in the Vietnamese children.vi
    dc.language.isoenvi
    dc.publisherH. : ĐHQGHNvi
    dc.relation.ispartofseriesVNU Journal of Science: Medical and Pharmaceutical Sciences;-
    dc.subjectObesityvi
    dc.subjectAnthropometric indicesvi
    dc.subjectVietnamese childrenvi
    dc.subjectMC4Rvi
    dc.titleAssociations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoivi
    dc.title.alternativeMối liên quan giữa đa hình đơn nucleotide rs17782313 của gen Melanocortin 4 Receptor với một số chỉ số nhân trắc của trẻ tiểu học bình thường và béo phì ở Hà Nộivi
    dc.typeArticlevi
    dc.identifier.doihttps:// doi.org/10.25073/2588-1132/vnumps.4107-
    Appears in Collections:Medical and Pharmaceutical Sciences


  • Associations of single nucleotide polymorphism rs17782313...
    • Size : 289,55 kB

    • Format : Adobe PDF

    • View : 
    • Download :