Introduction/overview -- Structural biology of the DJ-1 superfamily -- Expression of DJ-1 in patients with neurodegenerative diseases -- DJ-1 as an oncogene and its clinical significance -- Role of DJ-1 in fertilization -- Anti-oxidative stress function of DJ-1 -- Transcriptional regulation of DJ-1 -- Regulation of signal transduction by DJ-1 -- Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal -- DJ-1 as a biomarker of Parkinson's disease -- Roles of DJ-1 in diabetes mellitus -- Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases -- DJ-1 as an oncogene and promising target for cancer chemotherapy.
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Content Distribution
Introduction/overview -- Structural biology of the DJ-1 superfamily -- Expression of DJ-1 in patients with neurodegenerative diseases -- DJ-1 as an oncogene and its clinical significance -- Role of DJ-1 in fertilization -- Anti-oxidative stress function of DJ-1 -- Transcriptional regulation of DJ-1 -- Regulation of signal transduction by DJ-1 -- Protein repair by DJ-1 from glycation by glyoxal and methylglyoxal -- DJ-1 as a biomarker of Parkinson's disease -- Roles of DJ-1 in diabetes mellitus -- Therapeutic activities of DJ-1 and its binding compounds against neurodegenerative diseases -- DJ-1 as an oncogene and promising target for cancer chemotherapy.
