ArticleAuthors: Pham, Van Hao; Chu, Thi Xuan; Pham, Duc Thanh; Nguyen-Tran, Thuat; Nguyen, Hoang Hai; Mai, Anh Tuan (2018)
Surface modification of interdigitated DNA sensors by polypyrrole nanowires and gold nanoparticles has been analyzed systematically. Polypyrrole nanowires with diameter of 200 nm and length of 5mm were electrochemically synthesized on the gold surface of interdigitated electrodes and subsequently deco-rated with 20 nm gold nanoparticles. Electrochemical impedance spectroscopy and differential voltage measurements were conducted to detect DNA concentrations. We have observed a logarithmic depen-dence of analytical signals on the DNA concentration. A formula for estimating the limit of detection has been derived. Instead of using a conventional method in which a blank measurement is per...