Journal ArticleAuthors: Wensen, Jing; Lei, Feng; Bo, Wang; Weisong, Zhang; Kan, Peng (2021)
The osteoblast cell growth and cancer cell inhibition of titanium (Ti) metal implant coated with polyvinyl
alcohol (PVA) reinforced hydroxyapatite (HAP) composite were investigated. The fibrous composite of
PVA/HAP/folic acid (FA)/Methotrexate (MTX) was coated on the surface of a titanium plate and observed
with microscopy. During the PVA/HAP/FA/MTX composite's preparation, the functional changes and
crystalline phases were observed through Fourier-transform infrared spectroscopy and X-ray diffraction
analysis, respectively. The fiber composite had an average diameter of 19 nm and a greater mechanical
strength (9660 Pa) than that of pure HAP (4965 Pa), critical to the fibrous sc...